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The Substance is a 2024 body horror film written and directed by Coralie Fargeat. Starring Demi Moore, Margaret Qualley, and Dennis Quaid, the film follows Elisabeth Sparkle (Moore), a fading celebrity who, after being fired by her producer (Quaid) due to her age, uses a black market drug that creates a younger version of herself (Qualley) with unexpected side effects. The film is noted for its satirical elements and grotesque, hyperrealistic imagery. Motivated by societal pressures on women's b...

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